FDA approves first drug therapy for severe frostbite amputation risk

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Ear Drum

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New York Times: "Severe Frostbite Gets a Treatment That May Prevent Amputation"
The F.D.A. recently approved the first therapy for patients in danger of losing their toes, fingers and other exposed parts of the body.

By Matt Richtel
Feb. 24, 2024

The first time Dr. Peter Hackett saw a patient with frostbite, the man died from his wounds. It was in Chicago in 1971, and the man had gotten drunk and passed out in the snow, his fingers so frozen that gangrene eventually set in.

Dr. Hackett later worked at Mount Everest Basecamp, on Denali, Alaska, and now in Colorado, becoming expert in treating cold-weather injury. The experience was often the same: There was not much to do about frostbite, except rewarm the patient, give aspirin, amputate in severe cases and, more often, wait and accept that six months later the patient’s body might “auto-amputate” by naturally shedding a dead finger or toe.

His mentor in Anchorage used to say, “Frostbite January, Amputation July,” remembered Dr. Hackett, clinical professor at the Altitude Research Center at the University of Colorado’s Anschutz Medical Campus. “For centuries, there was nothing else to do.”

This month, the Food and Drug Administration approved the first therapy for treatment of severe frostbite in the country. The drug, iloprost, is given intravenously for several hours a day over a little more than week. It works by opening blood vessels to improve circulation, limiting inflammation and stopping the formation of platelet clumps that can stop circulation and kill tissue. Most at risk are a person’s toes, fingers, ears, cheeks and nose.

...

free to read link --
https://www.nytimes.com/2024/02/24/...e_code=1.ZE0.fDdK.mTbEahAeA6PB&smid=url-share

Moderator Note I locked this thread and linked it to the prior thread on this therapy (I dont seem to be able to move posts)
 
Last edited by a moderator:
New York Times: "Severe Frostbite Gets a Treatment That May Prevent Amputation"
The F.D.A. recently approved the first therapy for patients in danger of losing their toes, fingers and other exposed parts of the body.

By Matt Richtel
Feb. 24, 2024

The first time Dr. Peter Hackett saw a patient with frostbite, the man died from his wounds. It was in Chicago in 1971, and the man had gotten drunk and passed out in the snow, his fingers so frozen that gangrene eventually set in.

Dr. Hackett later worked at Mount Everest Basecamp, on Denali, Alaska, and now in Colorado, becoming expert in treating cold-weather injury. The experience was often the same: There was not much to do about frostbite, except rewarm the patient, give aspirin, amputate in severe cases and, more often, wait and accept that six months later the patient’s body might “auto-amputate” by naturally shedding a dead finger or toe.

His mentor in Anchorage used to say, “Frostbite January, Amputation July,” remembered Dr. Hackett, clinical professor at the Altitude Research Center at the University of Colorado’s Anschutz Medical Campus. “For centuries, there was nothing else to do.”

This month, the Food and Drug Administration approved the first therapy for treatment of severe frostbite in the country. The drug, iloprost, is given intravenously for several hours a day over a little more than week. It works by opening blood vessels to improve circulation, limiting inflammation and stopping the formation of platelet clumps that can stop circulation and kill tissue. Most at risk are a person’s toes, fingers, ears, cheeks and nose.

...

free to read link --
https://www.nytimes.com/2024/02/24/...e_code=1.ZE0.fDdK.mTbEahAeA6PB&smid=url-share
Moving to prior thread and locking this one
 
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